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Echelon Biosciences  EBI

 


Echelon Biosciences成立于1997年10月3日,總部坐落于在美國(guó)猶他州。從1997到2004,EBI主要用于政府的補(bǔ)助金以及產(chǎn)品的銷售收入來資助其研究工作。2005年初,EBI的依特鈉Zentaris購(gòu)買 (NAS:AEZS)的MEP抗感染,PI3激酶小分子程序,目錄業(yè)務(wù),與科學(xué)專業(yè)。2007年末,前沿科學(xué)公司(FSI)在洛根,猶他州購(gòu)買了EBI, 專業(yè)從事卟啉和硼化學(xué)。自公司成立以來以來,EBI保留了開發(fā)研究試劑脂質(zhì)新的檢測(cè)方法。不斷開拓**,從而推動(dòng)藥物研究的新發(fā)型。


Echelon Biosciences是美國(guó)有名免疫學(xué)產(chǎn)品供應(yīng)商,專業(yè)提供各種抗體、分析檢測(cè)試劑盒、抑制劑等產(chǎn)品,尤其擅長(zhǎng)以細(xì)胞信號(hào)、脂類代謝和標(biāo)記物研究為主的相關(guān)產(chǎn)品。為研究治療諸如癌癥、糖尿病、炎癥、感染和心腦血管疾病專家提供**有效工具。


Echelon Biosciences產(chǎn)品線

Lipid Kinases & Phosphatases

脂質(zhì)激酶和磷酸

Lipid-Protein Interaction Tools

脂蛋白質(zhì)相互作用工具

Lipid-Specific Assay Kits

脂質(zhì)特定檢測(cè)試劑盒

Lipid-Specific Antibodies & Binding Proteins

脂質(zhì)特定抗體和結(jié)合蛋白

Hyaluronic Acid & Collagen IV Assay Kits

透明質(zhì)酸和IV型膠原檢測(cè)試劑盒

Synthetic Inositol phosphates, Lipids, & Phospholipids

合成的磷酸肌醇,脂和磷脂


PI3-Kinase PI3-激酶

Echelon Biosciences可提供PI3-Kinase 實(shí)驗(yàn)解決全套方案,從分析服務(wù)到實(shí)驗(yàn)用抗體、酶和抑制劑等,**滿足科研需求。

專業(yè)系列

產(chǎn)品編號(hào)

特色產(chǎn)品

Kits

試劑盒

K-1000

PI3-K ELISA Kit

 K-1000S

PI3-K ELISA: Pico Assay

K-1100

PI3-K Fluorescence Polarization Kit

K-1300

PI3-K AlphaScreen®

 K-2700S

TRueFRET PI3-K Activity Assay

K-3000

Class III PI3-K ELISA Kit

Antibodies

抗體

Z-R015

Anti-huVps34 (Class III PI3-Kinase) Antibody for IP

Z-R016

Anti-huVps34 (Class III PI3-Kinase) Antibody for WB

Inhibitors

抑制劑

B-0021

Resveratrol (Class IA PI3-K Inhibitor)

B-0222

Wortmannin (PI3-Kinase Inhibitor)

B-0294

PI3-Kinase Inhibitor (LY294002)

B-0301

PI3-Kinase Gamma Inhibitor 1 (AS605240)

B-0302

PI3-Kinase Gamma Inhibitor 2 (AS604850

B-0303

PI3-Kinase Alpha Inhibitor 1 (PI-103)

B-0304

PI3-Kinase Alpha Inhibitor 2

Enzymes

 P27-18H

PI3-K (p-110 alpha/p85 alpha) Active Enzyme

 P28-10H

PI3-K (p-110 beta/p85 alpha) Active Enzyme


Lysolipids 血溶性脂類

Lysolipid Pathway                                            Synthetic Lysophosphatidic Acid (LPA)
◆ Inhibitors 抑制劑系列                                  ◆ Labeled 標(biāo)記物系列
◆ Ligands 配體系列                                        ◆ Ligands 配體系列
◆ Analogs 類似物系列                                    ◆ Saturated 底物系列
                                                                         ◆ Unsaturated 不飽和系列 

專業(yè)系列

產(chǎn)品標(biāo)號(hào)

特色產(chǎn)品

Kits試劑盒

 K-2800B

Lysophosphatidic Acid Competitive ELISA Kit

K-4100

Autotaxin Activity Assay

K-4200

Autotaxin Inhibitor Screening Kit

Enzymes酶

E-4000

Autotaxin Enzyme

Substrate底物

L-2000

FS-3 LysoPLD/Autotaxin Substrate

Inhibitors抑制劑

L-7416

LysoPLD/Autotaxin Inhibitor


Sphingolipids 鞘脂類

Synthetic Sphingolipids

◆ Sphingosine 鞘氨醇                           ◆ Ceramide 神經(jīng)酰胺

◆ Sphingosine 1 Phosphate (S1P ) 鞘氨醇磷酸酯     ◆ Sphingomyelin 鞘磷脂

◆ FTY720P 

專業(yè)系列

產(chǎn)品編號(hào)

特色產(chǎn)品

Kits

試劑盒

K-1900

Sphingosine 1 Phosphate ELISA Kit (S1P)

K-3500

Sphingosine Kinase 1 Activity Assay

K-1800

Sphingomyelinase Assay Kit

K-3200

Acid Sphingomyelinase Assay Kit

Enzymes

E-K068

Sphingosine Kinase 1, active

E-K069

Sphingosine Kinase 2, active

Inhibitors

抑制劑

B-0024

Sphingosine Kinase Inhibitor

 

產(chǎn)品編號(hào)

特色產(chǎn)品

S-400B

Sphingomyelin Biotin

 P-B0SM

Sphingomyelin Beads

S-6100

Sphingosine Beads

S-6110

Sphingosine 1 Phosphate Beads

 P-B00Ss

Sphingo Bead Sample Pack

 G-SM01

Sphingomyelin Grip (Equinatoxin)


Autotaxin(ATX) 自分泌運(yùn)動(dòng)因子

Echelon Biosciences是世界上**完整**提供Autotaxin(ATX) 和Autotaxin(ATX) 相關(guān)試劑的供應(yīng)商。

產(chǎn)品編號(hào)

特色產(chǎn)品

K-4100

Autotaxin Activity Assay Kit

K-4200

Autotaxin Inhibitor Screening Kit

 K-2800B

Lysophosphatidic Acid Competitive ELISA Kit

L-2000

FS-3 (LysoPLD / Autotaxin Substrate)

L-7416

BrP-LPA Autotaxin Inhibitor

E-4000

Autotaxin Enzyme



Echelon Biosciences目的在于進(jìn)一步發(fā)展的脂質(zhì)的細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)的關(guān)鍵代謝酶的科學(xué),它提供了對(duì)癌癥,心血管疾病疾病,糖尿病,炎癥,感染的潛在的藥物和診斷發(fā)展的新的和可行的目標(biāo)。


Echelon Biosciences為生命科學(xué)社區(qū)提供的產(chǎn)品包括:

抗體            分析檢測(cè)試劑盒

抑制劑           細(xì)胞信號(hào)產(chǎn)品

脂類代謝          標(biāo)記物


              Z-R015    Anti-huVps34 (Class III PI3-Kinase) Antibody for IP
抗體            Z-R016    Anti-huVps34 (Class III PI3-Kinase) Antibody for WB

               K-1000    PI3-K ELISA Kit
試劑盒       K-1000S    PI3-K ELISA: Pico Assay
                  K-1100    PI3-K Fluorescence Polarization Kit
                  K-1300    PI3-K AlphaScreen®
                  K-2700S    TRueFRET PI3-K Activity Assay
                  K-3000    Class III PI3-K ELISA Kit

              P27-18H    PI3-K (p-110 alpha/p85 alpha) Active Enzyme
酶               P28-10H    PI3-K (p-110 beta/p85 alpha) Active Enzyme
              B-0021    Resveratrol (Class IA PI3-K Inhibitor)
抑制劑        B-0222    Wortmannin (PI3-Kinase Inhibitor)
                   B-0294    PI3-Kinase Inhibitor (LY294002)
                   B-0301    PI3-Kinase Gamma Inhibitor 1 (AS605240)
                   B-0302    PI3-Kinase Gamma Inhibitor 2 (AS604850
                   B-0303    PI3-Kinase Alpha Inhibitor 1 (PI-103)
                   B-0304    PI3-Kinase Alpha Inhibitor 2


Echelon Biosciences Incorporated (EBI) was incorporated under the laws of the state of Utah as Echelon Research Laboratories, Inc. on October 3, 1997. Initially, Echelon Biosciences EBI was formed from a project under the Center for Cell Signaling, a State of Utah Center of Excellence, with the aim to further the science of lipid cell signaling and critical metabolic enzymes, which provide new and viable targets for the development of potential drugs and diagnostics for cancer, diabetes, inflammation, infections, and cardiovascular disease.


From 1997 through 2004, Echelon Biosciences EBI primarily used government grants and product sales revenues to fund its research efforts. In early 2005, EBI was purchased by Aeterna Zentaris (NAS: AEZS) for its MEP anti-infectives, PI3-Kinase small molecule program, catalog business, and scientific expertise. In late 2007, Frontier Scientific Incorporated (FSI) based in Logan, Utah purchased EBI. Specializing in porphyrin and boron chemistry, FSI opened the doors for expanded research.


Since 1997, Echelon Biosciences EBI has retained its commitment to developing novel assays and reagents for lipid research and beyond. At EBI’s core is the desire to innovate, thus pushing medicinal research to new limits. We look forward to providing scientists around the world with the tools they need to cure human disease states for years to come and we welcome any suggestions about how we can better do so.


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